g

g

g

the Lasso models were used for the analysis. In total 806 of 910

9%) top-ranked DEGs were deviated from the host genes of the

MSs for more than 1,000 genes. Only two (0.2%) top-ranked

ere within two gene order distances with the host genes of the

MSs. This means that the most important contribution towards

al methylation came from the differential expressions of remote

ll skewness tests were significant based on the chi-square test p

5. The R-square measures for E2M models constructed by four algorithms.

e 4.37 shows the densities of the base pair distances between the

on sites of the target DMSs and the bases of the top-ranked most

ng DEGs in four E2M models. Again, all were very severely

oward the right ends, meaning the most top-ranked influencing

r DMSs were remote in a very long distance in terms of the base

r instance, 890 of 910 (about 98%) top-ranked DEGs were more

mega base pairs apart from the methylation sites of the target

the Lasso models. Only two top-ranked DEGs were within one

pairs from the methylation sites of the target DMSs in the Lasso